TIMELAPSE VISION INC.

“To see things beyond ordinary vision”

this is what motivated us to capture the phenomena of life through a microscope.

Based on these microscopic images, we create original video content.

The discovery begins.

Bacterial phagocytosis by macrophage

TLV Lab

Images of Experiments

TLV has its own in-house experimental facilities and devices, so we can plan and implement any customized experiment or reproduce microscopic images of any specific phenomenon.

We handle microorganisms, such as cells, bacteria, viruses, or molds, according to Biosafety Level 2 (BSL2, P2).

We also provide supportive experiments, analysis, and photography for conference presentations and thesis submission.

Equipment

Clean bench, safety cabinet, CO2 incubator, constant temperature incubator, autoclave, dry heat sterilizer, gas replacement glove box, ultrapure water system, high-speed refrigerated centrifuge, clean isolator, breeding facility for experimental animals, deep freezer, liquid nitrogen, medical freezer/refrigerator, inverted microscope, and stereomicroscope.

Imaging Microscope

Inverted confocal laser scanning microscope, inverted phase contrast microscope, inverted differential interference contrast microscope, upright biological microscope, upright fluorescence microscope, research fluorescence stereomicroscope, and culture system for microscopy

TLV Conference Presentation / Thesis List

“Life in action”

Our “live imaging” is dedicated to conveying the wonders and motion of life.

By providing further insight into the phenomena of life and by making greater advancements in medicine and science, we are confident that we can positively contribute to the future of human beings.

International conference
2016　9th ISCTICO 2016 in Krakow, Poland.　A novel in vivo live imaging assay for endothelial nitric oxide production revealed improving effects of "Kangen-karyu" on blood flow.

2014　Society For Redox Biology and Medicine (SFRBM) 2014 annual meating in Seattle, USA Aspirin and /or NSAIDs-induced intestinal mucosal injury are required primary mucosal dysfunction caused by cellular reactive oxygen species production.

2014　8th International Symposium on Cell/Organoprotection 2014 in Budapest, Hungary
　　　NSAIDS- INDUCED ULCER FORMATIONS OF INTESTINAL MUCOSAE ARE NECESSARY
　　　BOTH PRIMARY SYSTEMIC DISFUNCTION OF MUCOSAL DEFENSE SYSTEM AND
　　　SECONDARY LOCAL ATTACK FACTORS

2013　Society for Free Radical Reserch Japan International Free Radicel Winter School in Muikamachi
　　　Reactive Oxigen make Cancer Dance

2012　American Society for Cell Biorogy (ASCB) 2012 annual meeting in San Fransisco, USA
　　　「Cancer Dance movement」 CellDance contest 3rd place

2012　7th International Symposium on Cell/Tissue Injury and Cytoprotection/Organoprotection in Hawaii, USA
　　　NSAIDs treatments involved ROS generation to induce epithelial cellular injuries in the mice intestine before lesions formation

2011　American Society for Cell Biorogy (ASCB) 2011 annual meeting in Denver, USA
　　　「Cancer Dance」 CellDance contest 1st place

2010　17th International The Society of Pure and Applied Coordination Chemistry (SPACC) in Kagoshima
　　　Power of Live-imaging, Seeing is Believing－Relation between NSAIDs induced small intestinal injuries and Reactive oxygen species －
Publication
2017　JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2017
　　　 High glucose-mediated overexpression of ICAM-1 in human vaginal epithelial cells
　　　 increases adhesion of Candida albicans.

2017　Evidence-Based Complementary and Alternative Medicine Volume 2017, Article ID 3620130, 7pages
　　　 Effect of Keishibukuryogan, a Japanese Traditional Kampo Prescription, on Improvement of
Microcirculation and Oketsu and Induction of Endothelial Nitric Oxide:A Live Imaging
Study.

2016　Calcif Tissue Int. 2017 Mar; 100(3): 286-97 (Epub 2016 Nov)
　　　 Bazedoxifene Ameliorates Homocysteine-Induced Apoptosis and Accumulation of Advanced
　　　 Glycation End Products by Reducing Oxidative Stress in Osteoblastic MC3T3-E1 Cells.

2016　Kangen-karyu raises surface body temperature through oxidative stress modification.
　　　 J. Clin. Biochem. Nutr. 2016 vol. 58 (3) :167–173

2016　Bazedoxifene Ameliorates Homocysteine-Induced Apoptosis and Accumulation of Advanced Glycation End Products by Reducing Oxidative Stress in MC3T3-E1 Cells.
　　　 Calcif Tissue Int. 2017 Mar; 100(3): 286-97 (Epub 2016 Nov)

2014　Advances in Microbiology Vol.4 No.11, September 2014.
　　　「Clarithromycin Attenuates the Bronchial Epithelial Damage Induced by Mycoplasma pneumoniae Infection.」

2014　Journal of Physiology and Pharmacology.Vol.65 No.3, June 2014
　　　「Indomethacin-induces generation of reactive oxygen species leads to epithelial cell injury before 　　the formation of intestinal lesions in mice.」

2014　J Clin Biochem Nutr. 2014 Jan;54(1):12-7.
　　　Mitochondrial reactive oxygen species accelerate gastric cancer cell invasion.

2012　Gastroenterology. 2012 Oct;143(4):1027-36.
　　　An orally administered redox nanoparticle that accumulates in the colonic mucosa and reduces colitis in mice.

About TLV

Image Production

The collaboration of our professional staff provides you products of the highest quality.

TLV is different from the rest due to a highly trained, professional staff in medical and life sciences.

We produce images that are both scientific and engaging.

Create through Connection

Research Group

Imaging Group

Our research group has developed its own unique technique for visualizing life phenomena under a microscope. We can also handle various objects such as living bodies, cells, bacteria, fungi, and others.

The imaging group is responsible for capturing the microscopic world through various microscopes and imaging devices. Besides being professionals in imaging microscopy, they also film on location or in the studio.

Direction Group

CG Creation Group

By assimilating and analyzing the content using their expert knowledge, our direction group delivers the final product as a story that is both easy to understand and intriguing.

TLV’s computer graphics (CG) developers then create new CG that combine the reality of representation with effective design through their examination of actual life phenomena.

The Flow of Our One-Stop System for Imaging Production

Planning

Experiment design

Scenario / CG storyboard creation

Experiment / Imaging microscopy

CG production

Filming on location

Editing

Sound recording

Delivery

Tailored to All Needs

Production is conducted with careful consideration so that the expressions used are appropriate for its target audience, which might include doctors, other medical professionals, patients, in-house training participants, or even general consumers. For example, the product can include commentary on cutting-edge information with experiment footage and realistic CG, explaining medical information in an easy-to-understand manner with simple illustrations, using drama to grab the viewer’s attention.

Our versatility can answer your every need, whether it is displaying a particular phenomenon under a microscope, visualizing a thesis experiment with microscopic images, adding more impact to an otherwise straightforward presentation of data introduction, or using microscopic images during lectures.