“To see things beyond ordinary vision”
this is what motivated us to capture the phenomena of life through a microscope.
Based on these microscopic images, we create original video content.
The discovery begins.
Bacterial phagocytosis by macrophage
Images of Experiments
TLV has its own in-house experimental facilities and devices, so we can plan and implement any customized experiment or reproduce microscopic images of any specific phenomenon.
We handle microorganisms, such as cells, bacteria, viruses, or molds, according to Biosafety Level 2 (BSL2, P2).
We also provide supportive experiments, analysis, and photography for conference presentations and thesis submission.
Clean bench, safety cabinet, CO2 incubator, constant temperature incubator, autoclave, dry heat sterilizer, gas replacement glove box, ultrapure water system, high-speed refrigerated centrifuge, clean isolator, breeding facility for experimental animals, deep freezer, liquid nitrogen, medical freezer/refrigerator, inverted microscope, and stereomicroscope.
Inverted confocal laser scanning microscope, inverted phase contrast microscope, inverted differential interference contrast microscope, upright biological microscope, upright fluorescence microscope, research fluorescence stereomicroscope, and culture system for microscopy
TLV Conference Presentation / Thesis List
“Life in action”
Our “live imaging” is dedicated to conveying the wonders and motion of life.
By providing further insight into the phenomena of life and by making greater advancements in medicine and science, we are confident that we can positively contribute to the future of human beings.
2016 9th ISCTICO 2016 in Krakow, Poland. A novel in vivo live imaging assay for endothelial nitric oxide production revealed improving effects of "Kangen-karyu" on blood flow.
2014 Society For Redox Biology and Medicine (SFRBM) 2014 annual meating in Seattle, USA Aspirin and /or NSAIDs-induced intestinal mucosal injury are required primary mucosal dysfunction caused by cellular reactive oxygen species production.
2014 8th International Symposium on Cell/Organoprotection 2014 in Budapest, Hungary
NSAIDS- INDUCED ULCER FORMATIONS OF INTESTINAL MUCOSAE ARE NECESSARY
BOTH PRIMARY SYSTEMIC DISFUNCTION OF MUCOSAL DEFENSE SYSTEM AND
SECONDARY LOCAL ATTACK FACTORS
2013 Society for Free Radical Reserch Japan International Free Radicel Winter School in Muikamachi
Reactive Oxigen make Cancer Dance
2012 American Society for Cell Biorogy (ASCB) 2012 annual meeting in San Fransisco, USA
「Cancer Dance movement」 CellDance contest 3rd place
2012 7th International Symposium on Cell/Tissue Injury and Cytoprotection/Organoprotection in Hawaii, USA
NSAIDs treatments involved ROS generation to induce epithelial cellular injuries in the mice intestine before lesions formation
2011 American Society for Cell Biorogy (ASCB) 2011 annual meeting in Denver, USA
「Cancer Dance」 CellDance contest 1st place
2010 17th International The Society of Pure and Applied Coordination Chemistry (SPACC) in Kagoshima
Power of Live-imaging, Seeing is Believing－Relation between NSAIDs induced small intestinal injuries and Reactive oxygen species －
2022 Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Volume 1868, Issue 4, 1 April 2022
Morphological and functional adaptation of pancreatic islet blood vessels to insulin resistance
is impaired in diabetic db/db micehttps://doi.org/10.1016/j.bbadis.2022.166339
2018 Biomaterials 167 (2018) 143e152
Novel angiogenesis therapeutics by redox injectable hydrogel - Regulation of local nitric oxide
generation for effective cardiovascular therapy.
2017 JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2017
High glucose-mediated overexpression of ICAM-1 in human vaginal epithelial cells
increases adhesion of Candida albicans.
2017 Evidence-Based Complementary and Alternative Medicine Volume 2017, Article ID 3620130, 7pages
Effect of Keishibukuryogan, a Japanese Traditional Kampo Prescription, on Improvement of
Microcirculation and Oketsu and Induction of Endothelial Nitric Oxide:A Live Imaging
2016 Calcif Tissue Int. 2017 Mar; 100(3): 286-97 (Epub 2016 Nov)
Bazedoxifene Ameliorates Homocysteine-Induced Apoptosis and Accumulation of Advanced
Glycation End Products by Reducing Oxidative Stress in Osteoblastic MC3T3-E1 Cells.
2016 Kangen-karyu raises surface body temperature through oxidative stress modification.
J. Clin. Biochem. Nutr. 2016 vol. 58 (3) :167–173
2016 Bazedoxifene Ameliorates Homocysteine-Induced Apoptosis and Accumulation of Advanced Glycation End Products by Reducing Oxidative Stress in MC3T3-E1 Cells.
Calcif Tissue Int. 2017 Mar; 100(3): 286-97 (Epub 2016 Nov)
2014 Advances in Microbiology Vol.4 No.11, September 2014.
「Clarithromycin Attenuates the Bronchial Epithelial Damage Induced by Mycoplasma pneumoniae Infection.」
2014 Journal of Physiology and Pharmacology.Vol.65 No.3, June 2014
「Indomethacin-induces generation of reactive oxygen species leads to epithelial cell injury before the formation of intestinal lesions in mice.」
2014 J Clin Biochem Nutr. 2014 Jan;54(1):12-7.
Mitochondrial reactive oxygen species accelerate gastric cancer cell invasion.
2012 Gastroenterology. 2012 Oct;143(4):1027-36.
An orally administered redox nanoparticle that accumulates in the colonic mucosa and reduces colitis in mice.
The collaboration of our professional staff provides you products of the highest quality.
TLV is different from the rest due to a highly trained, professional staff in medical and life sciences.
We produce images that are both scientific and engaging.
Create through Connection
Our research group has developed its own unique technique for visualizing life phenomena under a microscope. We can also handle various objects such as living bodies, cells, bacteria, fungi, and others.
The imaging group is responsible for capturing the microscopic world through various microscopes and imaging devices. Besides being professionals in imaging microscopy, they also film on location or in the studio.
CG Creation Group
By assimilating and analyzing the content using their expert knowledge, our direction group delivers the final product as a story that is both easy to understand and intriguing.
TLV’s computer graphics (CG) developers then create new CG that combine the reality of representation with effective design through their examination of actual life phenomena.
The Flow of Our One-Stop System for Imaging Production
Scenario / CG storyboard creation
Experiment / Imaging microscopy
Filming on location
Tailored to All Needs
Production is conducted with careful consideration so that the expressions used are appropriate for its target audience, which might include doctors, other medical professionals, patients, in-house training participants, or even general consumers. For example, the product can include commentary on cutting-edge information with experiment footage and realistic CG, explaining medical information in an easy-to-understand manner with simple illustrations, using drama to grab the viewer’s attention.
Our versatility can answer your every need, whether it is displaying a particular phenomenon under a microscope, visualizing a thesis experiment with microscopic images, adding more impact to an otherwise straightforward presentation of data introduction, or using microscopic images during lectures.
In vitro experiment
In vivo experiment
Action of an antibacterial drug to
〔Medicine density simulation in the living body〕
Bleeding from the gastric mucosa
by which an injury was done by NSAIDs
ABBOTT JAPAN CO., LTD.
Aichi Medical University Hospital
Asahi Kasei Pharma
Astellas Pharma Inc.
Chugai Pharmaceutical Co., Ltd.
Daiichi Sankyo Co., Ltd.
Eisai Co., Ltd.
Eli Lilly Japan K.K.
Fuji Television Network, Inc.
ISKRA INDUSTRY CO., LTD.
Japan Broadcasting Corporation(NHK)
McCann Healthcare Worldwide Japan, inc.
Merck Serono Co., Ltd.
Nobelpharma Co., Ltd.
Nomura Dairy Products Co., Ltd.
Novartis Pharma K.K.
Otsuka Pharmaceutical Co., Ltd.
Pfizer Japan Inc.
Taisho Toyama Pharmaceutical Co., Ltd.
Takeda Pharmaceutical Co., Ltd.
TORII PHARMACEUTICAL CO., LTD.
Tsukuba University of Technology
UCB Japan Co. Ltd
University of Tsukuba
For further inquiries, please use the contact form in Japanese site.
Our staff will contact you as soon as possible.
TIMELAPSE VISION INC.
PLAZA TORIYAMA 4F
5-23-11 Honcho, Shiki, Saitama
TEL : +81-48-487-9333
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